Publications

JN cover JP review cover-final

Titley, H.K., Brunel N., and Hansel, C. (2017). Toward a neurocentric view of learning. Neuron 95: 19-32.

Piochon, C., Titley, H.K., Simmons, D.H., Grasselli, G., Elgersma, Y., and Hansel, C. (2016). Calcium threshold shift enables frequency-independent control of plasticity by an instructive signal.  Proc. Natl. Acad. Sci. USA 113: 13221-13226.

Piochon, C., Kano, M., and Hansel, C. (2016). LTD-like molecular pathways in developmental synaptic pruning.  Nature Neurosci. 19: 1299-1310.

Grasselli, G., He, Q., Wan, V., Adelman, J.P., Ohtsuki, G., and Hansel, C. (2016). Activity-dependent plasticity of spike pauses in cerebellar Purkinje cells. Cell Reports 14: 2546-2553.

Kloth, A.D., Badura, A., Li, A., Cherskov, A., Connolly S.G., Giovannucci, A., Bangash, M.A., Grasselli, G., Penagarikano, O., Piochon, C., Tsai, P.T., Geschwind, D.H., Hansel, C., Sahin, M., Takumi, T., Worley, P.F., and Wang, S.S.H. (2015). Cerebellar associative sensory learning defects in five mouse autism models. eLife 4: e06085.

Piochon, C., Kloth, A.D., Grasselli, G., Titley, H.K., Nakayama, H., Hashimoto, K., Wan, V., Simmons, D.H., Eissa, T., Nakatani, J., Cherskov, A., Miyazaki, T., Watanabe, M., Takumi, T., Kano, M., Wang, S.S.-H., and Hansel, C. (2014). Cerebellar plasticity and motor learning deficits in a copy-number variation mouse model of autism. Nature Commun. 5: 5586.

Rinaldo, L. and Hansel, C. (2013): Muscarinic acetylcholine receptor activation blocks long-term potentiation at cerebellar parallel fiber-Purkinje cell synapses via cannabinoid signaling. Proc. Natl. Acad. Sci. USA 110: 11181-11186.

Ohtsuki, G., Piochon, C., Adelman, J.P. and Hansel, C. (2012): SK2 channel modulation contributes to compartment-specific dendritic plasticity in cerebellar Purkinje cells. Neuron 75, 108-120.

Belmeguenai, A, Hosy, E., Bengtsson, F., Pedroarena, C., Piochon, C., Teuling, E., He, Q., Ohtsuki, G., De Jeu, M.T., Elgersma, Y., De Zeeuw, C.I., Jörntell, H., and Hansel, C. (2010): Intrinsic plasticity complements LTP in parallel fiber input gain control in cerebellar Purkinje cells. J. Neurosci. 30, 13630-13643.

Schonewille, M., Belmeguenai, A., Koekkoek, S.K., Houtman, S.H., Boele, H.J., Van Beugen, B.J., Gao, Z., Badura, A., Ohtsuki, G., Amerika, W.E., Hosy, E., Hoebeek, F.E., Elgersma, Y., Hansel, C. and De Zeeuw, C.I. (2010): Purkinje cell-specific knock-out of the protein phosphatase PP2B impairs potentiation and cerebellar motor learning. Neuron 67, 618-628.

Hansel, C., de Jeu, M., Belmeguenai, A., Houtman, S.H., Buitendijk, G., Andreev, D., De Zeeuw, C.I. and Elgersma, Y. (2006): aCaMKII is essential for cerebellar LTD and motor learning. Neuron 51, 835-843.

Coesmans, M., Weber, J.T., De Zeeuw, C.I. and Hansel, C. (2004): Bidirectional parallel fiber plasticity in the cerebellum under climbing fiber control. Neuron 44, 691-700.

Hansel, C., Linden, D.J. and D’Angelo, E. (2001). Beyond parallel fiber LTD: the diversity of synaptic and non-synaptic plasticity in the cerebellum. Nature Neurosci. 4, 467-475.